The measure of a life well lived is arguably one that was at least aimed at rendering something constructive in the wake of the numerous sacrifices that the larger community of life has had to make for us to have lived at all. This delivery of something more than what is taken from the community that we collectively depend on to nourish us is the very essence of “bearing fruit”. This lesson is well crafted and clearly communicated through the structure of nature in so many ways – that we can count the seeds in an apple, but not the apples in a seed, as long as those seeds are cultivated in a nourishing environment to their mature potential. Fruit, in many forms, including social, can pay endless dividends that are greater than the sacrificial investment that must be made to bring them to fruition. Recognizing, and tending to these opportunities is the essence of life.
Some few of us humans get recognized as monuments of constructive contribution (whether deserved or not). Still others of us are also well known, but for another reason; because we have left a notorious wave of destruction in our wake. The overwhelming majority of us also get to express significance, either fruitful or notorious, in another way – not as individuals, but by way of participating in something greater than ourselves – by being part of some collective effort that either strengthens our chances to remain coherent and to thrive as a community going forward, or that threatens that hedge against chaos we must maintain so that we do not get swallowed by the antagonists that would destroy the ordered economy of relationships that renders integrity that we all depend on.
The significance of what we do in these larger bodies of influence, and the fruit they bear upon maturity, is not necessarily understood by those of us that participate in them as individuals. We may be completely oblivious to the significance and power of our contributions, constructive or destructive, yet we still play our roles. We can be an example of one of these collective efforts that has the capacity to pay constructive dividends, if we passionately search out and cultivate that opportunity over time. We can also be thankful for thousands and millions who have played roles in making our potential future little more fruitful by way of discovering and cultivating these opportunities.
Our preparedness, and in some cases, our willingness to bravely face and adapt to the challenges the environment places upon us as a species will determine whether or not it will endure, or sink beneath the threshold required by nature to maintain our integrity over time. Part of nature’s inherent demand is that we we find and cultivate the routines that produce the fruit that nourishes us. Part of facing this challenge is a willingness to face the unknown – to be explorers, and make this effort part of what drives our flexibility to turn the formerly unknown to an advantage, rather than continue to fear and avoid it until it devours us in our ignorance. It is this blend of flexibility and rigidity that we are best prepared to endure the waves of chaos that would otherwise erode our integrity.
We owe a committed debt of gratitude to those of us who make the sacrificial effort to illuminate the darkness and make it part of where we can dwell – those willing to search for and cultivate these undiscovered fruits. This ode to the many unsung heroes among us that are the lifeblood of our strength and vitality may not be praised in song often enough, but they nonetheless deserving of our thanks. Thank you to all you who are out there doing things to give back to this community we share and depend on for life.
Inside cells, protein “motors” act like trucks on tiny cellular highways to deliver life-sustaining cargoes.
Now a team led by Rutgers University-New Brunswick researchers has discovered how cells deploy enzymes to place traffic control and “roadway under construction” signs along cellular highways.
“To stay alive and function, every cell in our body needs to transport cargoes to the place they’re needed inside the cell, in the right amount and at the right time,” said Robert O’Hagan, lead author of a new study and assistant research professor in the Human Genetics Institute of New Jersey and the Department of Genetics at Rutgers University-New Brunswick. “So there has to be a lot of organization in how transport inside the cell is regulated, and now we know a lot more about how that happens.”
via How to Control Traffic on Cellular Highways – Neuroscience News
The basic nature expressed through biological systems all the way from the atoms and molecules that flit about in our cellular cytoplasm, through the organelles that serve as the institutional expressions of stability, producing and installing the various proteins we need, through the organs which have different capabilities that are dovetailed with each other, to the way we fit as species in the context of an ecosystem which we are part of and depend on for life must operate by the principle of nourishing and defending the continuing coherency of that entire system in order to remain coherent over time.
Whenever we focus at any level in a coherent biological system, we see the principle of the nourishment and the defense of coherency in the context of an environment with both nourishing and antagonistic agents at work. The coherent community of relationships of which we are composed dynamically differentiates friend from foe, and uses that perception to either call to service that which nourishes or defends itself against antagonists to remain coherent as a system over time.
Out of this fantastically complex blend of relationships, biology brings order to relative chaos. As biological creatures we are destined to engage in this process of nourishing and defending the coherency we depend on to continue. In this relational community we see the emergence of an implied purpose etched into all biological systems, whether or not these systems are at odds with each other. We call this global purpose expressed through biology by many names like survival instinct, nature, and so on, but the overarching unified purpose is that of nourishing and maintaining coherency over time. As byproducts of this theme we see acts of kindness, fruitful relationships as well as sacrifice in the mix. These various characters are the agents of balance and growth we depend on to realize our potential.
One of the prime necessary defenders in a local biological system like our own are the immune cells called “killer cells”. These cells target bacteria that are perceived as a threat and eradicate them so that they do not destroy the cooperative nourishing bonds that we depend on to remain coherent as a biological entity. Here is a closer look at how these soldiers of coherency that work and sacrifice on our behalf do their part in the tapestry of characters in this biological community that works to nourish and defend itself over time.
Microbial murder mystery solved
From the article: “…for the first time, researchers have caught killer cells red-handed in the act of microbial murder, observing them as they systematically killed three strains of microbes: E. coli and the bacteria responsible for causing Listeria infection and tuberculosis. The process inflicts bacterial cell death regardless of whether the environment contains oxygen or not… [The] findings… reveal that killer cells act methodically, shooting deadly enzymes into bacteria to “program” a complete internal breakdown and cell death.”
If we unpack the implications of the fact that a single celled parasite like Toxoplasma gondii can develop a strategy to modify mammalian neurophysiology and behaviors to suit its own biological ends, we can begin to appreciate the fact that the community of friends and foes in our local biological relationship field set the tone for what we experience as life.
There is a full spectrum of relationships that is possible in any given biological community that can span the spectrum from obligate (necessary) mutualism to parasitic and predatory relationship dynamics where seizing the fruit produced by other organisms is the core behavioral property of the organism.
Depending on the biological community’s bias toward cooperation involving mutual nourishment and common defense, or toward parasitic and predatory relational dynamics, the organism based community will tend toward homeostasis (balance), or instability. This makes whether or not we learn about, and act to appropriately tend the many organisms from which our local biology is composed is a key factor in whether balance or imbalance (health or disease) will happen. It also plays a key role in defining our identity and shaping experience of life. This makes understanding and cultivating the biological relational system we are part of a critical factor in effectively steering our experience of life.
Here is an article outlining how a number of parasitic and predatory organisms press their agenda within the larger biological community. It is important to remember that there is a full spectrum of relationship possibilities, some of which bring nourishment, strength and health or defense of the integrity of the system against disruptive agents.
I think we sometimes miss the profound and fascinating possibilities implied by this Niels Bohr quote:
“A physicist is just an atom’s way of looking at itself.”
There is no thing that we do on a macro scale that does not exist on a micro scale. Recurring echoes of self similarity with a blend of melodic dissonance is what makes up the magnificent symphony of structure we call biology. Smell is no exception:
Posted in Practice
Tagged Awareness, biological relationships, Biology, Community, Developmental biology, Language, life, Nature, Neuroscience, science, Systems biology