Category Archives: Wisdom

A Life Well Lived

The measure of a life well lived is arguably one that was at least aimed at rendering something constructive in the wake of the numerous sacrifices that the larger community of life has had to make for us to have lived at all. This delivery of something more than what is taken from the community that we collectively depend on to nourish us is the very essence of “bearing fruit”. This lesson is well crafted and clearly communicated through the structure of nature in so many ways – that we can count the seeds in an apple, but not the apples in a seed, as long as those seeds are cultivated in a nourishing environment to their mature potential. Fruit, in many forms, including social, can pay endless dividends that are greater than the sacrificial investment that must be made to bring them to fruition. Recognizing, and tending to these opportunities is the essence of life.

Some few of us humans get recognized as monuments of constructive contribution (whether deserved or not). Still others of us are also well known, but for another reason; because we have left a notorious wave of destruction in our wake. The overwhelming majority of us also get to express significance, either fruitful or notorious, in another way – not as individuals, but by way of participating in something greater than ourselves – by being part of some collective effort that either strengthens our chances to remain coherent and to thrive as a community going forward, or that threatens that hedge against chaos we must maintain so that we do not get swallowed by the antagonists that would destroy the ordered economy of relationships that renders integrity that we all depend on.

The significance of what we do in these larger bodies of influence, and the fruit they bear upon maturity, is not necessarily understood by those of us that participate in them as individuals. We may be completely oblivious to the significance and power of our contributions, constructive or destructive, yet we still play our roles. We can be an example of one of these collective efforts that has the capacity to pay constructive dividends, if we passionately search out and cultivate that opportunity over time. We can also be thankful for thousands and millions who have played roles in making our potential future little more fruitful by way of discovering and cultivating these opportunities.

Our preparedness, and in some cases, our willingness to bravely face and adapt to the challenges the environment places upon us as a species will determine whether or not it will endure, or sink beneath the threshold required by nature to maintain our integrity over time. Part of nature’s inherent demand is that we we find and cultivate the routines that produce the fruit that nourishes us. Part of facing this challenge is a willingness to face the unknown – to be explorers, and make this effort part of what drives our flexibility to turn the formerly unknown to an advantage, rather than continue to fear and avoid it until it devours us in our ignorance. It is this blend of flexibility and rigidity that we are best prepared to endure the waves of chaos that would otherwise erode our integrity.

We owe a committed debt of gratitude to those of us who make the sacrificial effort to illuminate the darkness and make it part of where we can dwell – those willing to search for and cultivate these undiscovered fruits. This ode to the many unsung heroes among us that are the lifeblood of our strength and vitality may not be praised in song often enough, but they nonetheless deserving of our thanks. Thank you to all you who are out there doing things to give back to this community we share and depend on for life.

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The Extended Body of Life We Depend on for Life

Although we tend to categorize biology in neat little abstract capsules like the names we might give a species, individual organisms, species and so on, do not respect these word based boundaries we give them. When we consider the community of relationships on which any part of a given biological system depends, we see the relationship membrane that defines what an organism needs to remain coherent over time extends beyond any local protein, organelle, or organ with a given species. Indeed the dependency extends beyond the membrane of any single organism or DNA profile to exist in the context of a larger body of life.

This larger body echoes the same relational dependencies that exist between cells and organs in a local biological economy such as a species, where mutual nourishment and protection of the coherency of the system is tended to by various means. In other words, a local biological economy depends on an extended family of relationships in order to continue over time, and this extended relational boundary, which operates by this same community principle, is a more accurate means of defining the membrane of a body of life than is any singular species within a local biological economy.

Like the roots of a tree extending inward to the soil, the networked lines of relational dependency a given organism requires to remain coherent over time extend both inward to include the mutually nourishing structures within the local membrane or skin of an individual organism, and outward to include a dependency on the larger economy of relationships that exists beyond the skin. Like an individual cell or organ, etc. the relationships that define an extended biological body also support the unified purpose of nourishing and protecting the continuation of the dynamic adaptive system as a whole. While there is some flexibility and redundancy, especially in larger systems, there is also a maximum threshold that, if exceeded, will result in the collapse of the system.

The same way the individual cells and organs in our body depend on each other for their mutual survival, this same community principle extends beyond singular organisms and stretches it roots of dependency into the larger body of life. There is no more pronounced, nor vital an illustration of this community principle that that which we see in bees, which depend on flowers, just as flowers depend on them, but this community principle also extends to the organisms that support the continuation of bees in less obvious ways. For instance, as illustrated in this article, certain fungi which operate as a vital organ in the larger body of life on which bees depend.

This message of mutual dependency, spoken through the biological economy of which bees and we are dependent, would be a valuable one for us to recognize and apply. It is yet one of the many valuable messages nature speaks through the structure of life.

In bee decline, fungicides emerge as improbable villain

https://phys.org/news/2017-11-bee-decline-fungicides-emerge-improbable.html

How to Control Traffic on Cellular Highways

glutamate-transportation-neurosciencenewsInside cells, protein “motors” act like trucks on tiny cellular highways to deliver life-sustaining cargoes.

Now a team led by Rutgers University-New Brunswick researchers has discovered how cells deploy enzymes to place traffic control and “roadway under construction” signs along cellular highways.

“To stay alive and function, every cell in our body needs to transport cargoes to the place they’re needed inside the cell, in the right amount and at the right time,” said Robert O’Hagan, lead author of a new study and assistant research professor in the Human Genetics Institute of New Jersey and the Department of Genetics at Rutgers University-New Brunswick. “So there has to be a lot of organization in how transport inside the cell is regulated, and now we know a lot more about how that happens.”

via How to Control Traffic on Cellular Highways – Neuroscience News

The Nature of Biological Systems

The basic nature expressed through biological systems all the way from the atoms and molecules that flit about in our cellular cytoplasm, through the organelles that serve as the institutional expressions of stability, producing and installing the various proteins we need, through the organs which have different capabilities that are dovetailed with each other, to the way we fit as species in the context of an ecosystem which we are part of and depend on for life must operate by the principle of nourishing and defending the continuing coherency of that entire system in order to remain coherent over time.

Whenever we focus at any level in a coherent biological system, we see the principle of the nourishment and the defense of coherency in the context of an environment with both nourishing and antagonistic agents at work. The coherent community of relationships of which we are composed dynamically differentiates friend from foe, and uses that perception to either call to service that which nourishes or defends itself against antagonists to remain coherent as a system over time.

Out of this fantastically complex blend of relationships, biology brings order to relative chaos. As biological creatures we are destined to engage in this process of nourishing and defending the coherency we depend on to continue. In this relational community we see the emergence of an implied purpose etched into all biological systems, whether or not these systems are at odds with each other. We call this global purpose expressed through biology by many names like survival instinct, nature, and so on, but the overarching unified purpose is that of nourishing and maintaining coherency over time. As byproducts of this theme we see acts of kindness, fruitful relationships as well as sacrifice in the mix. These various characters are the agents of balance and growth we depend on to realize our potential.

One of the prime necessary defenders in a local biological system like our own are the immune cells called “killer cells”. These cells target bacteria that are perceived as a threat and eradicate them so that they do not destroy the cooperative nourishing bonds that we depend on to remain coherent as a biological entity. Here is a closer look at how these soldiers of coherency that work and sacrifice on our behalf do their part in the tapestry of characters in this biological community that works to nourish and defend itself over time.

Microbial murder mystery solved

From the article: “…for the first time, researchers have caught killer cells red-handed in the act of microbial murder, observing them as they systematically killed three strains of microbes: E. coli and the bacteria responsible for causing Listeria infection and tuberculosis. The process inflicts bacterial cell death regardless of whether the environment contains oxygen or not… [The] findings… reveal that killer cells act methodically, shooting deadly enzymes into bacteria to “program” a complete internal breakdown and cell death.”

https://phys.org/news/2017-11-microbial-mystery.html

The Biological Community Defines Our Experience of Life

If we unpack the implications of the fact that a single celled parasite like Toxoplasma gondii can develop a strategy to modify mammalian neurophysiology and behaviors to suit its own biological ends, we can begin to appreciate the fact that the community of friends and foes in our local biological relationship field set the tone for what we experience as life.

There is a full spectrum of relationships that is possible in any given biological community that can span the spectrum from obligate (necessary) mutualism to parasitic and predatory relationship dynamics where seizing the fruit produced by other organisms is the core behavioral property of the organism.

Depending on the biological community’s bias toward cooperation involving mutual nourishment and common defense, or toward parasitic and predatory relational dynamics, the organism based community will tend toward homeostasis (balance), or instability. This makes whether or not we learn about, and act to appropriately tend the many organisms from which our local biology is composed is a key factor in whether balance or imbalance (health or disease) will happen. It also plays a key role in defining our identity and shaping experience of life. This makes understanding and cultivating the biological relational system we are part of a critical factor in effectively steering our experience of life.

Here is an article outlining how a number of parasitic and predatory organisms press their agenda within the larger biological community. It is important to remember that there is a full spectrum of relationship possibilities, some of which bring nourishment, strength and health or defense of the integrity of the system against disruptive agents.

http://www.the-scientist.com/?articles.view/articleNo/31536/title/Animal-Mind-Control/

Bees Talk Using Dance and Vibration as a Symbolic Language

Semiotics is the study of meaning-making, the study of using sign processes such as words, behaviors, shapes and the like (semiosis) as a means of transmitting meaningful information. This communication process is done by using symbols for coding and the capacity for decoding on the part of the receiver.
 
Semiotic language was once thought to be the sole domain of humans. As it turns out, we simply did not see the magnificent array of languages embedded in the structures and behaviors of organisms throughout the biological community. We missed it because we did not have the capacity to recognize (decode) it, so we attributed it to random behavior, or noise. The tide is beginning to turn on this previous paradigm as we are now exploring the many levels at which nature vibrantly communicates by semiotic means from cell signaling to the waggle dance of bees.
 
The “waggle dance” is a form of symbolic language spoken by honey bees to communicate the distance, direction and strength of a food source to the other bees.
 
From the article: “During the waggle phase the dancer produces trains of vibration pulses, which are detected by the follower bees via Johnston’s organ located on the antennae… The waggle dance represents a form of symbolic communication used by honeybees to convey the location of food sources via species-specific sound. The brain mechanisms used to decipher this symbolic information are unknown.”
 

Remembering the Sacrifice

Every exploration of the unknown poses both the promise of reward and the threat of failure and or destruction. This need to explore is sometimes driven by a circumstance where sitting still comes at the cost of being a continuing victim of an unyielding and harsh reality that continues to punish us, unless we explore its depths, to discover its secrets and to harness what was once our master.

In this exploration it is the brave pioneers who sometimes pay the ultimate price for the benefits that those of future generations can take for granted. Medical advance is one of these exploration fronts that demands this sacrifice, and many pioneering heroes lives have been lost in the pursuit of the value that comes understanding and bringing to order what was once chaos. To honor those that were willing as well as those that were simply caught in the crossfire of this ambivalent pursuit, this choice between the bloody and the bloodier, we should perhaps pause from time to time to remember their sacrifice fondly.

Here is one small example of that sacrifice that is the unfortunate cost of realizing the promises that, once discovered and harnessed, pay us all dividends from that point forward.

http://www.sciencealert.com/breakthrough-cancer-treatment-trials-put-on-hold-following-death-of-a-patient

An Atom’s Way of Looking at Itself

I think we sometimes miss the profound and fascinating possibilities implied by this Niels Bohr quote:

“A physicist is just an atom’s way of looking at itself.”

Powerful Influence from Small Changes

While this article is on *Brain Inflammation and Obesity* specifically, there seems to be a number of deeper implications if we apply a wide angle lens to the fact that certain infections, or microbiome populations, or traumas, etc. in the context of our complex biological system can shift behavioral expressions on more than physical scales. This influence on our relational landscape has a powerful influence on our experience of life. Extrapolated further we might begin to get a glimpse of how our evolution, history, culture and sense of identity might all be far more nebulous and arbitrary than we are used to believing.

https://www.labroots.com/trending/neuroscience/6586/brain-inflammation-obesity

Deeper Forms of Awareness

We sometimes confuse awareness with the meager and often inaccurate image that is conjured up by the constellation of verbal labels we have swimming around in our head; these things we use to produce a basic map of the world as well as concepts of self other truth and justice and so on… our words produce an image limited by their inability to serve as an accurate measure of the totality of what we experience, not just by a little, but by a huge margin.

Our verbal awareness is responsible for a certain portion of what we know, but this is by no means the only type of awareness, and is in fact a tiny sliver of it. In the midst of this misunderstanding we might miss the many things we know that we have no label for, these are often the drivers of our relationships in ways that our abstract symbols cannot identify, much less understand. Here’s a glimpse into some of the deeper waters of understanding that is embedded in our being.

https://medicalxpress.com/news/2017-07-infants.html