Tag Archives: Virus

Biological Influences on Identity Being and Personality

The influences that conspire to define what we experience as things like identity, being and personality type are built on a deep ocean of context based relationships which we have only begun to see with any real clarity, much less harness to our advantage. The currents of influence on which we ride have yet to be captured by the meager net of abstractions we feebly waggle into the depths in hopes of capturing something of value. Here’s a look at one tiny portion of this vast ocean of opportunity we have yet to discover and settle by way of leveraging our understanding toward progress.

An Ancient Virus Lurking in Our Genes Could Play an Important Role in Some Addictions

“…An unusual version of a retrovirus nestled between genes involved in brain chemistry is more common in individuals with a drug dependency than the rest of the population.*

https://www.sciencealert.com/endogenous-retrovirus-hk2-insertion-dopamine-gene-role-in-addiction

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Discovering Biological Friends and Foes

 

Not all viruses are dangerous. For instance; some are vital to how we function. The effects of endogenous retroviruses (those that stitch themselves into the human genome) are thought to have been essential for the evolutionary development of placental mammals as one example. Viruses can strategically trigger actions such as reproduction and, or go dormant depending on the biological climate at the time. The fact that cell replication in complex organisms like ourselves takes place and then goes dormant strategically may be due, at least in part, to the influence of viruses in the form of the genetic remnants of the traits that are now embedded in our genes. This, along with many other functions in human biology are parallel to, and could potentially be a result of, the influence of viral behaviors.

In addition to physiology, viruses are known to affect other behaviors such as those we categorize as psychological. The rabies virus is one well known virus that causes increased saliva flow and aggression in mammals. The borna disease virus can infect a number of animals, including humans. It has been known to cause hyperactivity, somnolence, depression and agitation. The point being; our experience as humans is built on a biological relationship economy that extends well beyond a stable set of genes. The relationship field from which we are composed can be cultivated, but it requires understanding how the whole process works. We have a long way to go, but we have made progress.

The spectrum of relationships in nature spans from constructive to destructive and that constructive vs. destructive trait depends on context. Some biological relationships contribute adaptive value, in these cases they are conserved. Viruses, like bacteria and so on can play destructive roles in the context of one system and a neutral or beneficial role in the context other systems. Like the role our various systems play from the respiratory system which carries nutrients in the form of oxygen to our cells, to the immune system which seeks out and destroys perceived antagonists, viruses also exist on this spectrum.. Some are lytic, in that they damage the relationship systems the host cell(s) depend on in such a way that the system is disrupted or destroyed. Understanding this destructive end of the biological spectrum, and how to remedy and or prevent these things from happening in the context of human systems is an important part of the further development of medicine. Here is a look at some of the work going on at the forefront of that discovery process:

𝗗𝗲𝘁𝗲𝗰𝘁𝗶𝗻𝗴 𝗗𝗮𝗻𝗴𝗲𝗿𝗼𝘂𝘀 𝗟𝗮𝘁𝗲𝗻𝘁 𝗩𝗶𝗿𝘂𝘀𝗲𝘀

“…Most people on the planet are thought to carry the HHV-6 virus, which doesn’t cause symptoms in the majority of cases. Antibodies to the virus can be found in anywhere from 95 to 100 percent of healthy individuals, showing that most adults have become infected at some point. It’s thought to be harmless, but in people that have undergone organ transplant, take immunosuppressants, or get a chlamydia infection, the virus can become active… Two types of the virus exist; HHV-6B tends to infect infants and HHV-6A is usually asymptomatic. It does, however, integrate into cellular DNA, where it can remain for a lifetime. It has recently been suggested that the virus can reactivate and may play a role in a variety of diseases including depression, bipolar disorder, schizophrenia, or Alzheimer’s… This work indicates that some prescriptions drugs might be able to reactivate HHV-6, leading to life-threatening danger for the patient. It may be very useful to identify these cases early.”

https://www.labroots.com/trending/microbiology/12741/detecting-dangerous-latent-viruses

Nature Echoes Nourish and Defend Behaviors on Many Scales

When our immune system sees a pathogen, something it perceives as harmful, it establishes ways to effectively neutralize or destroy that destructive agent. In doing this, it uses weapons (destructive agents), and vectors (vehicles) to carry the weapons it uses in defend to their appropriate location.

On a broader scale, this same defense of integrity through an “immune response strategy” may be what is going on at a larger scale in biological ecosystems. Since nature establishes defenses (things which destroy perceived pathogens) by establishing defensive weapons and looking for vectors to carry these destructive agents to their appropriate location in order to effect the “immune response”, why would we not expect to see this happening on different scales, from cell to body, to larger bodies of life?

The only difference in this relational dynamic that happens in a cell or single multicellular organisms that also may be happening in ecosystems may be the scale. This “immune response” may be also happening between larger bodies of life – bodies of life which transcend single organisms, and are constructed of networked metabolic structures that are stitched together through a vast array of species and subsystems within species – bodies of life that, although composed of many kinds of organisms, have a need to nourish itself, as well as protective skins and other defenses to protect itself, in addition to porous biological boundaries, the same way an individual cell or a larger organism does.

These larger bodies of life, which sometimes clash as a result of the existential debt nature demands for any coherent biological body – to nourish and protect itself, and to mount defenses against antagonists to that coherency. This may be the legend of the map that defines relationship landscape we see in biological ecosystems. It may also explain why, when there is less need for these defensive weapons to be carried to and fro to perceived pathogens in these larger bodies of life, that we also see these vectors less populated with these transgenic weapons, as we see in the case of mosquitoes in the rain forest, which tend to be less populated with the weapons of defense. Just a thought…

Disease-carrying mosquitoes rare in undisturbed tropical forests

From the article: “We found that fewer mosquito species known to carry disease-causing pathogens live in forested areas compared to disturbed ones… Mosquito species from altered forest sites are more likely to transmit disease than mosquitoes native to an area of mature tropical forest.”

Read more at: https://phys.org/news/2017-08-disease-carrying-mosquitoes-rare-undisturbed-tropical.html