Tag Archives: Systems biology

Biology Reveals Insights into Human Culture

This is an excellent documentary that illustrates how biological ecosystems find an equilibrium that is a suitable adaptive response to the environment. This means all the organisms that express nourishing and defense behaviors in a given ecosystem become specifically suited to the environment and each other. Islands are one of the places this biological balance is illustrated clearly; where the particulars of the environment along with the baseline biological ecosystem that inherited the island come to express a behavioral economy that is adaptive in that specific context. Islands with no large land predators may bring about flightless birds for instance because of the lack of need to fly away.

Christmas Island is an excellent illustration of how that biological equilibrium can be dramatically disrupted by a newcomer to the biological social economy. This disruption can expose weaknesses that are present because there was no need to build defenses against the strategies of the imported invader prior to its arrival. This is what drives biology’s own evolutionary expression of a “Game of Thrones” and may also be a good insight into the way the various human cultures evolved throughout the world – a reflection of populations finding equilibrium with the environment, reflecting its nature, coupled with the periodic need to adapt to “invaders” as we began to cross pollinate as a result of things like trade, climate shifts and so on, leading to the human version of “Game of Thrones”.

Powerful Influence from Small Changes

While this article is on *Brain Inflammation and Obesity* specifically, there seems to be a number of deeper implications if we apply a wide angle lens to the fact that certain infections, or microbiome populations, or traumas, etc. in the context of our complex biological system can shift behavioral expressions on more than physical scales. This influence on our relational landscape has a powerful influence on our experience of life. Extrapolated further we might begin to get a glimpse of how our evolution, history, culture and sense of identity might all be far more nebulous and arbitrary than we are used to believing.

https://www.labroots.com/trending/neuroscience/6586/brain-inflammation-obesity

How Smell Shapes Our Lives

There is no thing that we do on a macro scale that does not exist on a micro scale. Recurring echoes of self similarity with a blend of melodic dissonance is what makes up the magnificent symphony of structure we call biology. Smell is no exception:

The Strategy Employed by Nature to get Things Done

When it comes to accomplishing tasks in the face of various forms of adversity and an environment that would need to be cultivated or persuaded to move toward a specific goal, one way of breaking down the various strategies that are possible to do this is a concept called destinationist. A destinationist strategy accepts that the current state of affairs is not desirable and that change is necessary, but rather than being a determinist, where the strategy appears to be “all or none”, where arms are flapped or folded folded and scowls are formed and baying at the moon over the current circumstances – how wrong everybody is and how the world is not right is the de facto strategy, the destinationist uses a strategy which accepts the reality of the current landscape, and attempts to move in the correct direction using realistic doable steps, perhaps not knowing if full success is possible or warranted. Nature appears to have this destinationist philosophy as it attempts to do things to move in a certain direction, even though the current solution may not be perfect. One example it the following: “while having diarrhoea might be a nightmare, not having it could be an even worse fate.”

Here is an article detailing how the body uses a destinationist strategy to deal with stomach issues that comes with some pain, but is best given the overall picture.

http://www.sciencealert.com/scientists-just-realised-the-purpose-of-diarrhoea-is-way-more-complicated-than-we-thought

The Battlefront between Order and Chaos

The level of depth perception coupled with the predatory behavioral inclination of cancer produces a number of intricate strategies to advance its agenda to make itself the center and overtake the carrying capacity of the community of cells in which it lives, destroying the community (and itself) in the process. Cancer is like a seditious saboteur bent on destroying a nourishing sustainable system of relationships. This predatory antagonistic bias toward the relational harmony an organism depends on and the concerted effort of that community of harmonic relationships to defend against these destructive agents is a clear illustration of the battlefront between order and chaos we see expressed throughout nature.

One of the more intricate destructive strategies employed by cancer is to cause a kind of black flag type operation, where it tricks healthy cells into producing false viral signals so that they look like they are the problem to the immune system. This diverts the healthy system’s immune response resources toward a false problem redirecting energy that might otherwise be directed at the cancer, enabling it to carry on its work of seizing more resources for itself at the expense of the larger biological community.

Here is an article detailing this process:

Researchers Now Know How Cancers Force Other Cells to Make Fake Viruses

http://www.sciencealert.com/researchers-now-know-how-cancers-force-other-cells-to-make-fake-viruses

The Social Life of Plants

Plants have any number of methods to communicate both internally and externally in order to keep themselves informed and respond to their environment and developmental needs. They use this vast array of capacities to negotiate their way toward maturity and reproduction among other things. As it turns out, plants have a rich social life. They are for instance able to forge relationships with various benefactors in the plant and animal kingdoms and coordinate their effort, including the recruitment of other creatures, to ward off antagonists. They sense, and think without the means of a brain as we understand brains, yet they have the capacity to perceive and respond on remarkable levels which we are only beginning to understand. Here is a documentary on some of the recently discovered attributes of plants.

Cultivation Vs Domination

Science is increasingly recognizing that nature presents the most effective strategy as cultivation rather than domination – that the target is to cultivate a relationship field that attends to nourishing and protecting a community bound together with mutually beneficial ties as well as a willingness to defend the fruits that come from that community activity. We would do well to begin to apply this same cultivation vs domination principle to all aspects of life, from farming to interpersonal relationships to business and government, since our common ground is Earth.

From the article: “We have long believed that “good” immune cells recognise and defend against “bad” invaders. That’s why a large proportion of medicine has been directed at killing microbial enemies and conquering microbial infections.

This militaristic understanding of immunity reflected the culture of the 20th century, which was dominated by nation building and world wars between “us” and “them.” …a radical shift in understanding the relationship between humans and microorganisms occurred with the discovery that only 50% of the cells in our bodies are human. The rest are microbes, such as bacteria, yeasts (members of the fungus family), viruses, and even insects. Together, these make up the microbiome… Because we have evolved with microorganisms inside us, we now have specialised communities in our guts, on our skin, and in our mouths. Our microbes are understood to be so critical to our existence”

For more information: https://theconversation.com/essays-on-health-microbes-arent-the-enemy-theyre-a-big-part-of-who-we-are-79116

The Relationship Economy that Defines a Coherent Body of Life

The article link below describes how a single species of gut bacteria can reverse autism-related social behavior in mice.

The fact that a single organism can have so much influence on mouse behavior and experience is also a glimpse not only into the powerful biological drivers that result in what all organisms experience as life, but indeed what life experience is founded on. Our behaviors and experience, including whether and how much we are social, as well as whether or not we remain a coherent part of the biological economy over time and so on are based on the relational climate that forms as a result of a parliament of organisms and environmental conditions which together operate as a coherent body which influence behaviors and experience on multiple scales.

The notion that we are an individual species, defined by our local genetics and completely separate entities from other species is dissolving as a useful means to clearly define biology. A lens that sees biology as a relational economy that transcends our notions of individual species – one that renders the image that a coherent biological body consisting of organisms of many different genetic makeups networked together in diverse ways, forming a meta body, complete with a coherent integrated metabolism and the defense mechanisms to defend that integrity in the face of antagonists – is a more appropriate lens.

https://www.sciencedaily.com/releases/2016/06/160616140723.htm

On Free Will, Awareness and the Nature of Being

Many of us think we have agency – the capacity as individuals to perceive a certain portion of the local landscape of reality and use that as the basis to act independently, making our own free will choices. It comes as a surprise to some of us to discover that while an element of that perception of reality and corresponding response using a component of agency may be a piece of the puzzle, it is a small piece, if a piece at all.

Most of what we perceive and experience can be more accurately characterized as being “along for the ride” on a wave of relationship dynamics that occur on many scales, including molecular scales which are driven by the trillions of microbial life forms that live in and on us. In other words, we do not experience things due to what’s going on solely in our head, we experience things that stem from any number of sources known and unknown for which we manufacture what is in our mind a plausible explanation for those experiences.

Our capacity to produce plausible explanations is the real talent of our brain – producing things that are useful, but not necessarily things that are accurate. These explanations are inaccurate at best and often miss the mark completely, yet they produce a convincing picture, leaving us embraced in the comforting delusional cocoon of beliefs that may serve us, but do not correspond to the reality of the situation. Here is a small glimpse at the real world we so rarely get a glimpse of with our minds:

http://neurosciencenews.com/gut-bacteria-emotion-7013/

Where does Intelligence Reside?

The one on the left is a wasp, the one on the right is a moth. The question is; Where, how and on what level does the intelligence by which this mimicry takes place reside?

 

If we define intelligence as the ability to acquire and apply knowledge and skills, examples of mimicry like the example detailed in this story (linked below) have always left me wondering how a biological organism would be able to perceive and respond, at whatever level it takes, to recognize and assemble this cloak of deception without some capacity to sense “other minds” as well as a capacity to carry out a morphological change in response to that recognition of what’s going on in the mind of the other species…

For this moth to drape itself in the cloak of a wasp is a remarkable event, which we seem to be able to adequately describe, but our descriptions are certainly not explanations. In terms of explaining the event, what we typically call out, (adaptation, which is a description, not really an explanation) seems inadequate on its own without some kind of recognition of a sophisticated capacity for conceptualization and response embedded in the biological framework going on at some level that produces this sophisticated expression of adaptation. Just thinking out loud here.

https://phys.org/news/2017-02-biologists-years-textbook-wisdom-explanation.html